ncR2Met (2.0 version of the previous lncR2metasta), a manually curated database, aims at providing a comprehensive resource of ncRNA regulation in various cancer metastatic events, abbreviated as CMEs, such as cancer cell invasion, intravasation, extravasation, proliferation and so on, which may cooperatively facilitate malignant tumor spread and lead to massive patient deaths. It documents 1565 lncRNA-associated, 882 miRNA-associated, and 628 circRNA-associated entries for the ncRNA-CME associations during 50 CMEs across 63 human cancer subtypes. We believe that ncR2Met will act as a useful platform for elaborately understanding ncRNA functions in metastasis.
ncR2Met and LncR2metasta are offered to the public as a freely available resource.
Use and re-distribution of the data, in whole or in part, for commercial purposes requires explicit permission of the authors.
We kindly ask users to cite the ncR2Met and LncR2metasta paper in their resulting publications as:
(1) De’en Yu, Cheng Zhang, Yeman Zhou, Heng Yang, Chen Peng, Tongxing Lai, Xinghua Liao, Bo Li, Wensheng Deng, and Shihua Zhang, ncR2Met (lncR2metasta v2.0): a comprehensive database for experimentally supported ncRNAs during various cancer metastatic events, Journal, 2022
(2) Shihua Zhang, Xiaolong He, Rui Zhang, and Wensheng Deng, LncR2metasta: a manual curated database for experimentally supported lncRNAs during various cancer metastatic events, Briefings in bioinformatics, 2021, 22(3) 1-6.
This research was supported by grants from National Natural Science Foundation of China (Grant Nos. 62172312 and 31301248), and Fund of State Key Laboratory of Tea Plant Biology and Utilization at Anhui Agricultural University (SKLTOF20200102).